Lorena S. Beese: search on Z-Library

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1

Covalent protein–oligonucleotide conjugates by copper-free click reaction

Santoshkumar L. Khatwani, Jun Sung Kang, Daniel G. Mullen, Michael A. Hast, Lorena S. Beese, Mark D. Distefano, T. Andrew Taton

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

File:

PDF, 270 KB

2012

2

Structure of the Human MutSα DNA Lesion Recognition Complex

Joshua J. Warren, Timothy J. Pohlhaus, Anita Changela, Ravi R. Iyer, Paul L. Modrich, Lorena S. Beese

Journal:

Year:

2007

Language:

english

File:

PDF, 3.02 MB

english, 2007

3

The Crystal Structure of a Thermophilic Glucose Binding Protein Reveals Adaptations that Interconvert Mono and Di-saccharide Binding Sites

Matthew J. Cuneo, Anita Changela, Joshua J. Warren, Lorena S. Beese, Homme W. Hellinga

Journal:

Journal of Molecular Biology

Year:

2006

Language:

english

File:

PDF, 1.03 MB

english, 2006

4

Resistance mutations at the lipid substrate binding site of Plasmodium falciparum protein farnesyltransferase

Richard T. Eastman, John White, Oliver Hucke, Kohei Yokoyama, Christophe L.M.J. Verlinde, Michael A. Hast, Lorena S. Beese, Michael H. Gelb, Pradipsinh K. Rathod, Wesley C. Van Voorhis

Journal:

Molecular and Biochemical Parasitology

Year:

2007

Language:

english

File:

PDF, 313 KB

english, 2007

5

Crystallographic Analysis Reveals that Anticancer Clinical Candidate L-778,123 Inhibits Protein Farnesyltransferase and Geranylgeranyltransferase-I by Different Binding Modes †

Reid, T. Scott, Long, Stephen B., Beese, Lorena S.

Journal:

Year:

2004

Language:

english

File:

PDF, 763 KB

english, 2004

6

Caged Protein Prenyltransferase Substrates: Tools for Understanding Protein Prenylation

Amanda J. DeGraw, Michael A. Hast, Juhua Xu, Daniel Mullen, Lorena S. Beese, George Barany, Mark D. Distefano

Journal:

Chemical Biology & Drug Design

Year:

2008

Language:

english

File:

PDF, 294 KB

english, 2008

7

Protein farnesyltransferase

Park Hee-Won, Beese Lorena S

Journal:

Current Opinion in Structural Biology

Year:

1997

Language:

english

File:

PDF, 713 KB

english, 1997

8

Structural Adaptations that Modulate Monosaccharide, Disaccharide, and Trisaccharide Specificities in Periplasmic Maltose-Binding Proteins

Matthew J. Cuneo, Anita Changela, Lorena S. Beese, Homme W. Hellinga

Journal:

Journal of Molecular Biology

Year:

2009

Language:

english

File:

PDF, 1.66 MB

english, 2009

9

Crystal Structures of Human Exonuclease I with DNA Provides Insight into Substrate Selectivity and Mechanism

Orans, Jillian, McSweeney, Elizabeth, Modrich, Paul, Beese, Lorena S.

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 41 KB

english, 2011

10

The basis for K-Ras4B binding specificity to protein farnesyl-transferase revealed by 2 Å resolution ternary complex structures

Stephen B Long, Patrick J Casey, Lorena S Beese

Journal:

Year:

2000

Language:

english

File:

PDF, 209 KB

english, 2000

11

Obituary

Orans, Jillian, McSweeney, Elizabeth, Modrich, Paul, Beese, Lorena S.

Journal:

Year:

1986

Language:

english

File:

PDF, 198 KB

english, 1986

12

Microtubule structure at 18 Å resolution

Beese, Lorena, Stubbs, Gerald, Cohen, Carolyn

Journal:

Journal of Molecular Biology

Year:

1987

Language:

english

File:

PDF, 799 KB

english, 1987

13

Structures of Mismatch Replication Errors Observed in a DNA Polymerase

Sean J. Johnson, Lorena S. Beese

Journal:

Year:

2004

Language:

english

File:

PDF, 569 KB

english, 2004

14

Structure of microtubules with reduced hydration

Beese, Lorena, Stubbs, Gerald, Thomas, Joseph, Cohen, Carolyn

Journal:

Journal of Molecular Biology

Year:

1987

Language:

english

File:

PDF, 4.11 MB

english, 1987

15

Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis

Weina Wang, Homme W. Hellinga and Lorena S. Beese

Journal:

Proceedings of the National Academy of Sciences

Year:

2011

Language:

english

File:

PDF, 1.48 MB

english, 2011

16

Structure-based design of robust glucose biosensors using a Thermotoga maritima periplasmic glucose-binding protein

Yaji Tian, Matthew J. Cuneo, Anita Changela, Birte Höcker, Lorena S. Beese, Homme W. Hellinga

Journal:

Protein Science

Year:

2007

Language:

english

File:

PDF, 531 KB

english, 2007

17

Conversion of Protein Farnesyltransferase to a Geranylgeranyltransferase †

Terry, Kimberly L., Casey, Patrick J., Beese, Lorena S.

Journal:

Year:

2006

Language:

english

File:

PDF, 635 KB

english, 2006

18

Crystal Structure of Farnesyl Protein Transferase Complexed with a CaaX Peptide and Farnesyl Diphosphate Analogue †

Strickland, Corey L., Windsor, William T., Syto, Rosalinda, Wang, Lynn, Bond, Richard, Wu, Zhen, Schwartz, Jeffrey, Le, Hung V., Beese, Lorena S., Weber, Patricia C.

Journal:

Year:

1998

Language:

english

File:

PDF, 373 KB

english, 1998

19

Crystal structures of the Klenow fragment of DNA polymerase I complexed with deoxynucleoside triphosphate and pyrophosphate

Beese, Lorena S., Friedman, Jonathan M., Steitz, Thomas A.

Journal:

Year:

1993

Language:

english

File:

PDF, 3.32 MB

english, 1993

20

Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase

Hsu, Gerald W., Ober, Matthias, Carell, Thomas, Beese, Lorena S.

Journal:

Year:

2004

Language:

english

File:

PDF, 332 KB

english, 2004

21

Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family

Jillian Orans, Elizabeth A. McSweeney, Ravi R. Iyer, Michael A. Hast, Homme W. Hellinga, Paul Modrich, Lorena S. Beese

Journal:

Year:

2011

Language:

english

File:

PDF, 2.04 MB

english, 2011

22

Crystal structure of a pol α family DNA polymerase from the hyperthermophilic archaeon Thermococcus sp. 9°N-7

A.Chapin Rodriguez, Hee-Won Park, Chen Mao, Lorena S Beese

Journal:

Journal of Molecular Biology

Year:

2000

Language:

english

File:

PDF, 1.14 MB

english, 2000

23

Reaction path of protein farnesyltransferase at atomic resolution

Long, Stephen B., Casey, Patrick J., Beese, Lorena S.

Journal:

Year:

2002

Language:

english

File:

PDF, 484 KB

english, 2002

24

Rapid Analysis of Protein Farnesyltransferase Substrate Specificity Using Peptide Libraries and Isoprenoid Diphosphate Analogues

Wang, Yen-Chih, Dozier, Jonathan K., Beese, Lorena S., Distefano, Mark D.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 1.20 MB

english, 2014

25

The Closing Mechanism of DNA Polymerase I at Atomic Resolution

Miller, Bill R., Beese, Lorena S., Parish, Carol A., Wu, Eugene Y.

Journal:

Year:

2015

Language:

english

File:

PDF, 4.12 MB

english, 2015

26

NIH Public Access

Degraw, Amanda J, Hast, Michael A, Xu, Juhua, Mullen, Daniel, Beese, Lorena S, Distefano, Mark D

Year:

2009

Language:

english

File:

PDF, 866 KB

english, 2009

27

Sensing and Processing of DNA Interstrand Crosslinks by the Mismatch Repair Pathway

Kato, Niyo, Kawasoe, Yoshitaka, Williams, Hannah, Coates, Elena, Roy, Upasana, Shi, Yuqian, Beese, Lorena S., Schärer, Orlando D., Yan, Hong, Gottesman, Max E., Takahashi, Tatsuro S., Gautier, Jean

Journal:

Year:

2017

Language:

english

File:

PDF, 1.98 MB

english, 2017

28

Crystal structures of the fungal pathogen Aspergillus fumigatus protein farnesyltransferase complexed with substrates and inhibitors reveal features for antifungal drug design

Mabanglo, Mark F., Hast, Michael A., Lubock, Nathan B., Hellinga, Homme W., Beese, Lorena S.

Journal:

Protein Science

Year:

2014

Language:

english

File:

PDF, 994 KB

english, 2014

29

Electron microscopy of thin filaments decorated with a Ca2+-regulated myosin

Roger Craig, Andrew G. Szent-Györgyi, Lorena Beese, Paula Flicker, Peter Vibert, Carolyn Cohen

Journal:

Journal of Molecular Biology

Year:

1980

Language:

english

File:

PDF, 16.94 MB

english, 1980

30

Kinetic Analysis of Zinc Ligand Mutants of Mammalian Protein Farnesyltransferase †

Fu, Hua-Wen, Beese, Lorena S., Casey, Patrick J.

Journal:

Year:

1998

Language:

english

File:

PDF, 79 KB

english, 1998

31

Observing Translesion Synthesis of an Aromatic Amine DNA Adduct by a High-fidelity DNA Polymerase

Hsu, Gerald W., Kiefer, James R., Burnouf, Dominique, Becherel, Olivier J., Fuchs, Robert P. P., Beese, Lorena S.

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 976 KB

english, 2004

32

Crystal structure of a thermostable Bacillus DNA polymerase l large fragment at 2.1 Å resolution

James R Kiefer, Chen Mao, Connie J Hansen, Scott L Basehore, Holly H Hogrefe, Jeffrey C Braman, Lorena S Beese

Journal:

Year:

1997

Language:

english

File:

PDF, 797 KB

english, 1997

33

Crystallographic Analysis of CaaX Prenyltransferases Complexed with Substrates Defines Rules of Protein Substrate Selectivity

T. Scott Reid, Kimberly L. Terry, Patrick J. Casey, Lorena S. Beese

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 1.00 MB

english, 2004

34

Crystal Structures of the Anticancer Clinical Candidates R115777 (Tipifarnib) and BMS-214662 Complexed with Protein Farnesyltransferase Suggest a Mechanism of FTI Selectivity †

Reid, T. Scott, Beese, Lorena S.

Journal:

Year:

2004

Language:

english

File:

PDF, 587 KB

english, 2004

35

Cocrystal Structure of Protein Farnesyltransferase Complexed with a Farnesyl Diphosphate Substrate †,‡

Long, Stephen B., Casey, Patrick J., Beese, Lorena S.

Journal:

Year:

1998

Language:

english

File:

PDF, 140 KB

english, 1998

36

Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I

Shi, Yuqian, Hellinga, Homme W., Beese, Lorena S.

Journal:

Proceedings of the National Academy of Sciences

Year:

2017

Language:

english

File:

PDF, 2.01 MB

english, 2017

37

Dissecting the Differences between the α and β Anomers of the Oxidative DNA Lesion FaPydG

Florian Büsch, J. Carsten Pieck, Matthias Ober, Johannes Gierlich, Gerald W. Hsu, Lorena S. Beese, Thomas Carell

Journal:

Chemistry - A European Journal

Year:

2008

Language:

english

File:

PDF, 322 KB

english, 2008

38

3-Aminopyrrolidinone Farnesyltransferase Inhibitors: Design of Macrocyclic Compounds with Improved Pharmacokinetics and Excellent Cell Potency

Bell, Ian M., Gallicchio, Steven N., Abrams, Marc, Beese, Lorena S., Beshore, Douglas C., Bhimnathwala, Hema, Bogusky, Michael J., Buser, Carolyn A., Culberson, J. Christopher, Davide, Joseph, Ellis-H

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 877 KB

english, 2002

39

Ligand-induced conformational changes in a thermophilic ribose-binding protein

Matthew J Cuneo, Lorena S Beese, Homme W Hellinga

Journal:

BMC Structural Biology

Year:

2008

Language:

english

File:

PDF, 1.95 MB

english, 2008

40

The Mechanism of the Translocation Step in DNA Replication by DNA Polymerase I: A Computer Simulation Analysis

Andrei A. Golosov, Joshua J. Warren, Lorena S. Beese, Martin Karplus

Journal:

Year:

2010

Language:

english

File:

PDF, 1.75 MB

english, 2010

41

Conversion of Tyr361β to Leu in Mammalian Protein Farnesyltransferase Impairs Product Release but Not Substrate Recognition †

Spence, Rebecca A., Hightower, Kendra E., Terry, Kimberly L., Beese, Lorena S., Fierke, Carol A., Casey, Patrick J.

Journal:

Year:

2000

Language:

english

File:

PDF, 148 KB

english, 2000

42

Discrimination between Right and Wrong Purine dNTPs by DNA Polymerase I from Bacillus stearothermophilus

Trostler, Michael, Delier, Alison, Beckman, Jeff, Urban, Milan, Patro, Jennifer N., Spratt, Thomas E., Beese, Lorena S., Kuchta, Robert D.

Journal:

Year:

2009

Language:

english

File:

PDF, 2.14 MB

english, 2009

43

10.1038/34693

Beese, Lorena S., Kiefer, James R., Mao, Chen, Braman, Jeffrey C.

Journal:

Year:

1998

Language:

english

File:

PDF, 526 KB

english, 1998

44

A Farnesyltransferase Acts to Inhibit Ectopic Neurite Formation in C. elegans

Carr, David, Sanchez-Alvarez, Leticia, Imai, Janice H., Slatculescu, Cristina, Noblett, Nathaniel, Mao, Lei, Beese, Lorena, Colavita, Antonio, Hendricks, Michael

Journal:

Year:

2016

Language:

english

File:

PDF, 3.38 MB

english, 2016

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